PET/CT增强在鼻咽癌头颈部淋巴结转移的应用价值

Application value of enhanced PET/CT in scanning for cephalic and cervical lymph node metastasis of nasopharyngeal carcinoma

目的:研究PET/CT同机CT增强一站式扫描对鼻咽癌患者头颈部淋巴结转移的检测价值。方法:对61例确诊鼻咽癌患者行PET/CT同机CT对比剂增强一站式扫描,分析PET图像、CT图像和PET/CT增强图像对淋巴结检测的特点,分成3组数据,对比各组对颈部淋巴结转移诊断的差异。结果:61例患者共发现213个病灶,其中CT组发现阳性病灶137个,阴性病灶76个,灵敏度83.8%,特异性86.4%;PET组发现阳性病灶156个,阴性病灶57个,灵敏度95.5%,特异性86.2%;PET/CT增强组发现阳性病灶153个,阴性病灶60个,灵敏度99.3%,特异性98.3%。结论:PET/CT增强扫描在鼻咽癌头颈部淋巴结转移的诊断中,无论是对淋巴结的检出,还是在良恶性判断方面都有重要的应用价值。

Objective To study on the application value of positron emission tomography （PET）/CT fusion scanning in the detection of cephalic and cervical lymph node metastasis of nasopharyngeal carcinoma. Methods The PET/CT fusion scanning with contrast medium was conducted for 61 patients diagnosed as nasopharyngeal carcinoma. The characteristics of PET images, CT images and enhanced PET/CT scanner fusion images for the detection of lymph node were analyzed and divided into 3 groups of data. The differences of the diagnosis of cephalic and cervical lymph node metastasis were compared between the 3 groups. Results Totally, 213 lesions were found in 61 patients. In CT group, 137 positive lesions and 76 negative lesions were found, with a sensitivity of 83.8% and a specificity of 86.4%. In PET group, 156 positive lesions and 57 negative lesions were found, with a sensitivity of 95.5% and a specificity of 86.2%. In enhanced PET/CT group, 153 positive lesions and 60 negative lesions were found, with a sensitivity of 99.3% and a specificity of 98.3%. Conclusion Enhanced PET/CT scanning has important application value in the diagnosis of cephalic and cervical lymph node metastasis of nasopharyngeal carcinoma, no matter for the detection of lymph node or the judgment of benign and malignant tumor.