摘要
目的探讨胸腺五肽联合抗结核治疗与肺结核复发的相关性及危险因素。方法分析2004年1月至2011年12月收治的428例经细菌学证实为肺结核的病例,经随访2年以上,选择10项临床、放射及治疗等指标分析对早/晚复发的影响。结果全组有19例复发,复发率为4.43%,早期复发(小于等于1年)12例,晚期复发(大于1年)7例。胸肽腺联合标准一线抗结核药物的早期复发率为1.77%,晚期复发率为1.18%。高细菌学含量和空洞是早期复发的危险因素,而年龄和糖尿病则是晚期复发的危险因素。结论辨别肺结核复发的危险因素对于选择治疗方案有积极的意义。
Objective To investigate thymopentin combined with anti - tuberculosis drugs therapy and the risk factors for recurrence of pulmo-nary tuberculosis parient. Methods A total of 428 patients receiving anti - tuberculosis therapy in our hospital from January 2004 to December 2011 were enrolled in this study to review the clinical characteristics, radiology features and treatment, ten parameters contributing to the recurrence were ana-lyzed. Results Nineteen patients （4.43% ） had recurrence. Of the 19 patients, 12 patients had early recurrence and 7 patients had the late one. High bacterial loads and cavitations disease were risk factors for early recurrence while higher age and diabetes mellitus were risk factor for the late recur-rence. Conclusions The identification of significant risk factors for recurrence may enable better selection of treatment options.
出处
《医疗装备》
2016年第18期1-3,共3页
Medical Equipment
关键词
肺结核
胸腺五肽
复发
危险因素
P ulmonary tuberculosis
Thymopentin
Recurrence
Risk factor
