绵萆薢三萜皂苷类成分研究

Triterpenoid Saponins from the Rhizome of Dioscorea spongiosa

为了解绵萆薢(Dioscorea spongiosa)的化学成分,从其70%乙醇水溶液提取物中分离鉴定了8个化合物,经理化性质和波谱数据分析分别鉴定为:20(S)-人参皂苷Rh1(1)、人参皂苷Rg1(2)、人参皂苷Re(3)、三七皂苷R1(4)、人参皂苷Rd(5)、人参皂苷Rb1(6)、常青藤皂苷元3-O-α-L-吡喃阿拉伯糖苷(7)和木通皂苷D(8)。化合物1、2、3、5和6为首次从该种植物中分离得到,化合物7和8为首次从薯蓣属植物中分离得到。

In order to understand the chemical constituents of Dioscorea spongiosa, eight triterpenoid saponins were obtained from 70% Et OH extract of its rhizome. On the basis of their physicochemical and spectral data, these saponins were identified as 20（S）-ginsenoside Rh1（1）, ginsenoside Rg1（2）, ginsenoside Re（3）, notoginsenoside R1（4）, ginsenoside Rd（5）, ginsenoside Rb1（6）, hederagenin-3-O-α-L-arabinopyranoside（7）, and akebiasaponin D（8）. Among them, compounds 1, 2, 3, 5 and 6 were isolated from this species for the first time, and compounds 7 and 8 were obtained from the genus Dioscorea for the first time.