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胎盘多肽、鹿瓜多肽联合抗风湿类药物治疗类风湿性关节炎临床观察 被引量:5

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摘要 目的:在慢作用抗风湿药的基础上联合应用胎盘多肽、鹿瓜多肽,旨在进一步提高类风湿性关节炎(RA)疗效。方法:RA患者75例,随机分为观察组50例和对照组25例。对照组给予来氟米特10mg,口服1次/d,甲氨蝶呤片5mg,口服2次/周;观察组在对照组用药基础上静滴胎盘多肽8ml,鹿瓜多肽24mg,1次/d,连用10d,2月后进行疗效评定。结果:两组患者在DAS28评分及HAQ评分均有明显改善,观察组优于对照组(P<0.05),两组患者ESR、CRP、RF、CCP均有下降,观察组优于对照组(P<0.05)。结论:胎盘多肽、鹿瓜多肽联合DMARDs治疗RA提高了临床疗效,减轻了DMARDs的副作用,提高了患者的依次性和耐受性,值得临床推广应用。
出处 《陕西医学杂志》 CAS 2016年第10期1413-1414,共2页 Shaanxi Medical Journal
基金 陕西省科技厅资助课题(2015JM8397)
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