中药结合穴位埋线治疗功能性消化不良伴焦虑抑郁状态患者的疗效观察

Clinical observation of effects of thread-embedding therapy combined with traditional Chinese medicine in treatment of functional dyspepsia accompanied by anxiety and depression

目的:观察中药结合穴位埋线疗法治疗功能性消化不良伴焦虑、抑郁状态患者的疗效。方法:选择功能性消化不良伴焦虑抑郁状态患者60例,随机分为治疗组和对照组,每组各30例。治疗组患者给予穴位埋线加中药治疗;对照组患者给予单纯中药治疗。两组患者均经过4周的治疗。治疗前后,采用焦虑自评量表(SAS)、抑郁自评量表(SDS)量表和医生报告结局量表(Clinician-deported outcomes,CRO)对两组患者进行评定,并进行比较。结果:治疗后,治疗组患者的总有效率96.67%;对照组总有效率90%,组间差异有统计学意义(P<0.05);两组患者的SAS、SDS评分均较治疗前明显降低(P<0.05),组间差异无统计学意义(P>0.05)。结论:中药结合穴位埋线治疗功能性消化不良伴焦虑抑郁状态患者的疗效优于单纯中药治疗。

Objective： To observe clinical therapeutic effects of thread-embedding therapy combined with traditional Chinese medicine（ TCM） in treatment of functional dyspepsia（ FD） accompanied by anxiety and depression. Methods： 60 patients with FD accompanied by anxiety and depression were selected and randomly divided into treatment group（ thread-embedding therapy combined with TCM） and control group（ the monotherapy of TCM）,with 30 patients in each group. The treatments lasted for 4 weeks,then these patients were evaluated with the self-rating depression scale（ SDS）,self-rating anxiety scale SAS and the Clinician-deported outcome（ CRO） scale before and after the treatment,and the results of the two groups were compared. Results： After the treatment,the total effective rates of treatment group and control group were 96.67% and 90%,respectively,and the difference between the two groups was statistically significant（ P〈0.05）. The SAS and SDS scores of the two groups after the treatment were obviously reduced（ P〈0.05）,but the differences between the two groups were not statistically significant（ P〉0.05）. Conclusions： Thethread-embedding therapy combined with TCM in the treatment of FD accompanied by anxiety and depression is superior to single TCM.