糖尿病采用尿总蛋白肌酐比和胱抑素-C的临床观察

Clinical observation on diabetes with urinary protein creatinine ratio(TPCR) and cystatin C

目的:糖尿病患者以尿总蛋白肌酐比(TPCR)和胱抑素-C(Cys C)为指标评定糖尿病早期肾损伤的临床应用价值,进一步为临床诊断提供参考依据。方法:选取收治的糖尿病患者60例为试验组,另选取健康人群60例作为对照组,在试验过程中监测所有患者TPCR、Cys C、亮氨酸氨基肽酶(LAP)、白蛋白(ALB)等指标。结果:试验组与对照组患者TPCR及Cys C指标差异有统计学意义(P<0.05),ALB、LAP指标差异无统计学意义(P>0.05)。结论:检测患者TPCR和Cys C对临床诊断糖尿病早期肾损伤具有重要意义,值得进一步推广和使用。

Objective To analyze of diabetic patients to U- TP creatinine ratio（ tpcr） and cystatin C as an index evaluation the clinical value of early renal damage in diabetes. Method 60 cases of diabetic patients were selected as experimental group.60 cases of another healthy population were selected as control group. In the experimental process monitoring all patients total urinary protein to creatinine ratio（ tpcr）,serum cystatin C（ Cys C）,lap,ALB. Results The difference of TPCR,Cys C between the experimental group and the control group was significantly higher than ALB,LAP（ P〈0. 05）. Conclusion Detection of U- TP creatinine ratio（ tpcr） and cystatin C for clinical diagnosis of diabetic early renal damage is of great significance,it is worth further promotion and use.