不同表层角膜屈光手术方式后疼痛及角膜刺激症状比较

The Comparison of Pain and Corneal Irritation by Different Methods of Surface Corneal Refractive Surgery

目的探究不同表层角膜屈光手术方式后疼痛及角膜刺激症状的差异。方法按术式不同将方便选取该院2014年6月—2015年12月期间行PRK(准分子激光屈光性角膜切削术)、LASEK(乙醇法准分子激光上皮瓣下角膜磨镶术)及Epi-LASIK(微型上皮刀法准分子激光上皮瓣下角膜磨镶术)的150例患者分别设为A、B、C3组,各50例(100眼),对比三组角膜刺激症状及疼痛指数的差异。结果术后第1天,A、B两组出现角膜刺激症状分为别有91眼、86眼,疼痛指数分别为2.95、2.77,两组对比差异有统计学意义(P<0.05),C组出现角膜刺激症状有60眼、疼痛指数为1.01,与A、B组相比差异有统计学意义(P<0.05);术后2、3 d,A组出现角膜刺激症状有79眼、49眼,疼痛指数为2.04、0.91,与B、C组相比差异有统计学意义(P<0.05),且B组与C组相比差异无统计学意义(P>0.05)。结论不同表层角膜屈光手术术后疼痛及角膜刺激症状具有一定的差异,术后疼痛是引起患者不适的主要因素之一。

Objective To discuss the difference of pain and corneal irritation by different methods of surface corneal refractive surgery. Methods Convenient selection to divided the 150 cases of patients from June 2014 — December 2015 into the group A, B and C as the different methods of surgery that included the PRK（photorefractive keratectomy）, LASEK（Laser Assisted Subepithelial Keratomileusis） and Epi-LASIK（Excimer laser epithelial keratomileusis）, each 50 cases（100 eyes）,to compared the difference of corneal irritation and aches-and-pains index of them. Results At the 1st day of surgery, A, B groups divided corneal irritation do not have 91, 86, pain index were 2.95,2.77, there was statistical significance（P〈0.05）,group C corneal irritation has 60, the pain index was 1.01,compare with the group A and B, there was statistical significance（P〈0.05）. At the 2 nd and 3 rd day of surgery,A group of corneal irritation have 79, 49, pain index 2.04,0.91,there was statistical significance（P〈0.05）, but to compared the group B and C, there was no statistical significance（P〈0.05）.Conclusion The has a certain difference of pain and corneal irritation by different methods of surface corneal refractive surgery, the postoperation pain is the main reason that caused the discomfort of patients.