吗啡联合咪达唑仑对急危重症患者ICU内镇痛镇静的效果探究

Morphine Combined Midazolam for Patients in the ICU Critical Patients Analgesia Calming Effect is Explored

目的评估在ICU内危急重症患者的镇痛镇静治疗中运用咪达唑仑+吗啡的效果及其有关情况。方法方便选择2015年5月—2016年5月因患有危急重症而进入该院ICU接受诊疗的73例患者,随机将其划分作对照、实验两组,对照组36例予以咪达唑仑+曲马多实施镇痛镇静性治疗,实验组37例予以咪达唑仑+吗啡实施镇痛镇静性治疗,经探究两种用药法的运用情况,比对两组镇静镇痛方面的疗效。结果实验组37例在用药治疗48 h后的VAS、Ramasay评估分是(2.1±0.84)分、(5.2±0.29)分,优越于对照组36例的(3.9±1.28)分、(2.9±0.37)分,差异有统计学意义(P<0.05)。另外,实验组病例持续通气时间、住院天数是(4.5±1.12)、(6.1±1.43)d,优越于对照组的(7.1±1.15)、(9.8±2.39)d,对比差异有统计学意义(P<0.05)。结论在ICU危重症患者的镇痛、镇静治疗当中选用吗啡+咪达唑仑联治方法,既能获得较佳成效,又可减少人工通气及住院天数,值得进一步推荐及运用。

Objective To assess emergency and severe cases in patients in the ICU of analgesia in calm treatment using midazolam plus the effect of morphine and its related situation. Methods Convenient selection in May 2015 — May 2016 for emergency and severe cases and into our hospital ICU with diagnosis and treatment of 73 patients, to contrast the division, experiment two groups at random, control group 36 cases with midazolam plus tramadol implementation analgesia tranquilizing therapy, the experimental group 37 cases with midazolam ＋ morphine analgesia tranquilizing therapy, through to explore the application of two kinds of medicine method, compare the curative effect of two groups of sedation analgesia.Results 37 cases in 48 hours after treatment of VAS, Ramasay evaluation points is（2.1 ± 0.84）,（5.2±0.29） points, is superior to the control group of 36 cases（3.9 ± 1.28）,（2.9±0.37） points and differences（P〈0.05）. In addition, the experimental group cases ventilation duration, hospitalization days is（4.5±1.12）,（6.1±1.43）d, is superior to control group（7.1± 1.15）d,（9.8± 2.39）d, compare the differences（P〈0.05）. Conclusion Critically ill patients in the ICU of analgesia, sedation therapy selection of morphine plus midazolam league method, which can obtain better results, and can reduce artificial ventilation and hospitalization days, deserves further recommend and use.