基于AGREE Ⅱ的2型糖尿病指南和共识质量评价

Evaluation and Comparison of Practice Guidelines and Consensus on Type 2 Diabetes:A Systematic Appraisal

目的旨在评价现有2型糖尿病临床指南和专家共识,以此为基础了解临床指南和专家共识之间的差距,对专家共识的制定提出建议。方法系统检索Pub Med、Embase、中国知网(CNKI)、万方数据知识服务平台、中国生物医学文献服务系统(Sino Med)等数据库。根据纳入排除标准筛选国内外关于2型糖尿病药物治疗的指南和共识。采用AGREEⅡ评估工具评价指南和共识的方法学质量。结果纳入的指南间质量有一定差距,但整体质量仍远高于共识。指南在范围和目的、清晰性两个领域得分较高,在严谨性和应用性领域得分较低。共识在6个领域的得分均较低。结论造成指南和共识间差异的主要原因是共识在方法学上存在较大缺陷,因此本研究推荐使用快速建议指南代替共识。

OBJECTIVE To evaluate the quality of now available clinical guidelines and consensus statements on type 2 diabetes. Based on this assessment, the comparison of guidelines and consensuses is made to give some suggestions on the methods of making these documents. METHODS PubMed, Embase, CNKI, Wanfang, SinoMed and guideline websites were systematically searched. Literatures were screened according to defined criteria for including. AGREE Ⅱ was used to instrument assess the quality of the guide- lines and consensuses. RESULTS The result showed that the quality of included guidelines is various, but the overall quality of guidelines is still higher than consensuses. Guidelines got high scores in scope and purpose domain and clarity of presentation domain, but low scores in rigor of development domain and applicability domain. Consensus statements got low scores in all 6 domains. CONCLUSION The main reason for the difference is consensuses have poor methodology. Rapid advice guidelines were suggested as an alternative for consensus statements.