肝内型持续性右脐静脉胎儿预后及与门静脉变异的关系

Outcome of the Fetuses with Intrahepatic Persist Right Umbilical Vein and the Relationship with Portal Vein Variation

目的:探讨产前超声诊断肝内型持续性右脐静脉(PRUV)胎儿在一般孕妇人群中的发生率、预后及与门静脉变异的关系。方法:回顾性分析2011年1月至2015年7月在上海交通大学附属第六人民医院产前检查并分娩或终止妊娠的诊断为PRUV胎儿的孕妇49例的临床资料。结果:PRUV胎儿49例均为肝内型,发生率0.32%(1:313)。其中,单纯型肝内型PRUV胎儿45例,占91.84%,预后都良好;4例(8.16%)合并胎儿畸形,其中2例合并严重心血管畸形并中孕引产,2例分别合并室间隔缺损及结肠闭锁,新生儿期手术治疗,预后良好。49例PRUV胎儿肝内门静脉的形态发生变异,门静脉左支如正常胎儿的右支呈分枝状,而门静脉右支如正常胎儿左支呈"工"字型。结论:绝大部分肝内型PRUV胎儿预后良好,但门静脉有变异。

Objective：To investigate the incidence and clinical pregnancy outcome of intrahepatic persistent right umbilical vein（PRUV） fetus,and the relationship with portal vein variation. Methods：Retrospective analysis the data of 49 consecutive cases carried prenatal ultrasonic examination and delivery or pregnancy termination in the sixth people＇s hospital affiliated to Shanghai jiaotong university from January 2011 to July 2015. Results： Of 49 fetuses diagnosed with PRUV（occurring rate 0. 32% ）, all cases were intrahepatic PRUV. In the 49 cases of PRUV ,45（91.84% ） were isolated,and they were in good pregnancy outcomes. And 4（8. 16% ） were associated with anomaly. Severe cardiovascular malformation happened in 2 cases, and ventricular septal defect and colonic atresia happened in 1 case respectively. There were portal vein variations in PRUV fetuses：left branch as normal fetus＇s right branch of branching, and right portal vein branch such as normal fetal left branch showed ＂工＂ shape. Conclusions ：While majority of PRUV cases carry excellent prognosis,the portal vein of some cases have variation.