从“热毒作祟致瘀”探析刘霞治疗小儿过敏性紫癜经验

Clinical study of Xiefei Lishui method for the treatment of chronic heart failure accompanied with diuretic resistance

总结刘霞教授从"热毒作祟致瘀"治疗小儿过敏性紫癜的临床经验。强调"热毒"是过敏性紫癜发病的根本病因,"热毒作祟致瘀,瘀滞化热,瘀贯始终"是病机关键。治当凉血活血、滋阴清热,结合小儿自身特点,临证用药兼顾脾胃,贵在加减,使"血止不留瘀,血行不伤正,凉润不碍脾"。

Objective To observe the clinical efficacy of Xiefei Lishui （ reducing lung and eliminating water） method for chronic heart failure patients accompanied with diuretic resistance. Methods 60 patients with chronic heart failure accompanied with diuretic resistance were divided into the control group and the treatment group of 30 cases respectively with random number table method. Both two groups received the same basic treatment, while the treatment group was also treated with Heart Failure No. 3 Formula which had an effect of reducing lung and eliminating water additionally. The total treatment for both groups lasted 2 weeks. The scores of Traditional Chinese Medicine（TCM） symptoms, left ventricular ejection fraction （LVEF） and 6 rain walking test （6MWT） were measured in both groups before and after treatment. Results Compared with that of before treatment in both groups, TCM symptom scores, LVEF, and 6 MWT after treatment were significantly improved, and moreover, the improvement in the treatment group was markedly superior to that in the control group （ P 〈 0. 05 ）. Conclusion TCM methods of Xiefei Lishui can significantly improve the clinical symptoms and heart function in CHF patients with diuretic resistance.