补骨脂化学成分及生物活性研究进展

Research progress of the chemical constituents and bioactivity of Psoralea corylifolia

补骨脂是一种重要的药用植物,具有抗菌、抗肿瘤、抗氧化、抗炎和免疫调节等活性。其植物体内含有多种化学物质,包括补骨脂素、异补骨脂素、补骨脂酚、补骨脂定、巴库查耳酮、补骨脂二氢黄酮甲醚等香豆素类、黄酮类、单帖酚类化合物。本文就补骨脂化学成分及生物活性的研究作一综述。

Psoralea corylifolia is an important medicinal plant, it has antibacterial, antitumor, antioxidant, anti- flammatory, antifungal and immunomodulatory activity. A wide range of chemical compounds, including psolaren, isopsolaren, bakuchiol, psoralidin,bakuchalcone, bavachinin, flavones, volatile oils and lipids are found in different parts of the plant. The present review aims to give a detailed survey of the literature on the chemical constituents and bioactivities of plant Psoralea corylifolia.