摘要
本文介绍了以邻氯硝基苯为起始原料,经氯磺化、缩合、水解、还原合成2-氨基苯酚-4-(2'-羧基)磺酰苯胺工艺,讨论了氯磺化及催化加氢反应对收率影响因素,确定最佳工艺条件,最终产物含量大于98%,总收率大于80%。
2- [ （ 3-amino - 4- hydroxyphenyl） sulfonylamino ] benzoic acid was synthesized from o- chloronitrobenzene by chlorosulfona- tion, condensation, hydrolysis, and reduction. And the react conditions of chlorosulfonation and reduction were also investigated. The optimum condition for synthesize of 2-[ （3-amino-4-hydroxyphenyl）sulfonylamino ] benzoic acid was obtained. The over all yield of 2- [ （3-amino-4-hydroxyphenyl） sulfonylamino] benzoic acid was 85%, and the purity was 98%.
出处
《染料与染色》
CAS
2016年第4期22-25,18,共5页
Dyestuffs and Coloration
