高通量血液透析对糖尿病肾病血液透析患者预后的影响

Effect of High Flux Hemodialysis on the Prognosis of Patients With Diabetic Nephropathy

目的观察高通量血液透析对糖尿病肾病血液透析患者预后的影响。方法选取我院收治的68例糖尿病肾病血液透析患者,随机分为两组,各34例,两组患者均给予常规基础治疗,在此基础上对照组给予低通量血液透析治疗,观察组采取高通量血液透析治疗,对比两组心脑血管事件发生率与透析后1年、3年生存率。结果观察组心脑血管事件发生率低于对照组,且3年后生存率高于对照组,差异均有统计学意义(P<0.05)。结论应用高通量血液透析可显著降低糖尿病肾病血液透析患者心脑血管事件发生率,提高患者远期生存率。

Objective To observe the effect of high flux hemodialysis on prognosis of hemodialysis patients with diabetic nephropathy. Methods 68 cases of diabetic nephropathy in our hospital were selected, random grouping, each of 34 cases, two groups of patients were given conventional basic treatment, on the basis of this, the control group was treated with low flux hemodialysis, the observation group was treated with high flux hemodialysis, compared the incidence of cardiovascular and cerebrovascular events in the two groups and the survival rate of 1 years and 3 years after dialysis. Results The incidence of cardiovascular events in the observation group was lower than that of the control group, and the survival rate of the observation group was higher than that of the control group after 3 years, and the difference was statistically significant （P〈0.05）. Conclusion Application of high flux hemodialysis can significantly reduce the incidence of cardiovascular and cerebrovascular events in patients with diabetic nephropathy, and improve the long-term survival rate.