持久性发疹性斑状毛细血管扩张症临床及组织病理特点

Clinical and histopathological features of telangiectasia macularis eruptiva perstans

目的:分析持久性发疹性斑状毛细血管扩张症的临床和组织病理特点。方法:对该8例持久性发疹性斑状毛细血管扩张症患者的临床资料(包括临床、组织病理表现及治疗情况)进行回顾性分析。结果:所有患者均为男性,皮损好发于胸部与上肢,Darier征阳性1例。皮损组织病理检查:表皮角化过度,真皮浅层可见浅层毛细血管扩张,Giemsa染色阳性。8例患者均无系统性损害,其中1例患者有乙型肝炎病史。口服酮替芬等治疗效果不明显,采用补骨脂素长波紫外线(PUVA)治疗,症状可缓解。结论:临床表现结合皮损组织病理学检查为诊断该病的依据。

Objective： To analyze the clinical and histopathological features of telangiectasia macularis eruptiva perstans. Methods： We retrospectively analyzed the clinical and histopalhologieal data of 8 cases with telangiectasia macularis eruptiva perstans, which were diagnosed and treated in our hospital. Results： All patients were males. The skin lesions were mainly distributed in the upper chest and the arms. Darier＇s sign was positive in one case. Histopathological examination showed telangiectasia and increased number of Giemsa positive mast cells around the capillaries in the upper dermis. No systemic involvement occurred in these patients. One patient had a history of hepatitis. Oral ketotifen fumarate did not improve the condition, while PUVA therapy relieved symptoms. Conclusion： The diagnosis of telangiectasiamacularis eruptiva perstans can be made according to its clinical manifestations and histopathological features.