中药治疗转移性骨肿瘤疼痛临床研究

Clinical research of TCM treating pain of metastatic bone tumors

目的探讨中药治疗转移性骨肿瘤疼痛的临床效果。方法选取2014年1月至2016年1月在我院治疗的转移性骨肿瘤疼痛患者60例,随机分为对照组和观察组,每组30例。对照组给予氨酚羟考酮片1片/次,1次/6h,同时根据患者NRS评分对给药剂量进行调整。观察组在对照组基础上给予本院药剂科煎制的中药"扶正解毒散"。比较两组疼痛缓解率、体力状况评分、疼痛评分、镇痛药物的用量、爆发痛的发生次数和患者对镇痛效果满意度。结果观察组疼痛缓解有效率、体力状况评分和镇痛效果满意度方面明显优于对照组,爆发痛发生率、治疗全程镇痛药物的用量和NRS评分显著低于对照组。结论中药治疗转移性骨肿瘤疼痛的临床效果显著,值得临床推广。

Objective To study the curative effect of TCM treating pain of metastatic bone tumors.Methods A total of 60 cases patients with pain of metastatic bone tumors were randomly divided into control group and observation group,with 30 cases in each group.Control group received foreign medicine only,and observation group received foreign medicine combined with TCM.Rate of pain relief,Karnofsky scoring,pain scores,dosage of analgesic drug,frequency of breakthrough pain,and satisfaction of analgesic effect were compared.Results The rate of pain relief,Karnofsky scoring and satisfaction of analgesic effect in the observation group were better.The frequency of breakthrough pain,the NRS scores and the dosage of analgesic drug in the observation group were less than the control group.Conclusion Traditional Chinese medicine could improve the analgesic effect of metastatic bone tumors,reduce the dosage of analgesic drug,and increase the satisfaction of analgesic effect.