厄贝沙坦与尼莫地平治疗老年高血压疗效观察

Efficacy and Safety of Irbesartan and Nimodipine Injection in Treatment of Senile Hypertension

目的:探讨厄贝沙坦与尼莫地平注射液治疗老年高血压患者疗效与安全性。方法:选取我院2014年1—12月老年高血压患者60例,采用随机数字表法分为2组,各30例。观察组采用尼莫地平注射液治疗,对照组采用厄贝沙坦治疗。结果:治疗前,2组SBP、DBP水平比较无显著性差异(P>0.05);治疗后,全部患者SBP、DBP水平明显低于治疗前,且观察组SBP、DBP水平明显低于对照组(P<0.05);观察组SBP达标时间与DBP达标时间明显短于对照组(P<0.05)。2组药物不良反应率比较无显著性差异(P>0.05)。结论:尼莫地平注射液治疗老年高血压患者疗效显著,药物安全性较高,值得临床推广应用。

Objective：To investigate the efficacy and safety of irbesartan and nimodipine injection in treatment of senile hypertension.Methods：60 cases of senile hypertension were selected from our hospital between January 2014 to December 2014.All patients were divided into two groups by random number table method, 30 cases in each group.The control group was administered with irbesartan while the observation group was injected with nimodipine.Results：Before treatment, SBP and DBP levels had no statistical difference between the two groups （ P〉0.05）;after treatment, SBP and DBP levels in all patients were significantly lower than those of pretherapy, and in the observation group showed significantly lower SBP and DBP than in the control group （P〈0.05）.The time to reach SBP or DBP standard was significantly shorter in the observation group than that in the control group.No significant difference was found in drug adverse reaction between the two groups （P〈0.05）.Conclusion：The treatment of senile hypertension with nimodipine injection is effective and safe.It is worthy of clinical promotion.