朗格罕斯细胞组织细胞增生症1例

One case of langerhans cell histiocytosis

对已收治的1例朗格罕斯细胞组织细胞增生症(langerhans cell histiocytosis,LCH)的临床资料进行回顾性分析。本文所诉病例以皮疹及外耳道渗液为最初临床表现,继而出现头部肿块及肝酶异常,因其表现的非特异性而误诊为湿疹及头部囊肿。最终经组织活检及免疫组织化学检查确诊为LCH。临床如遇不明原因的体表肿块、反复皮疹、顽固中耳炎、长期不规则发热及肝脾淋巴结增大患者均应考虑到LCH,宜尽快进行组织活检及免疫组织化学检查,以免误诊及漏诊。

To retrospectively analyze the clinical data of one admitted case of Langerhans cell histiocytosis （LCH）. The initial clinical manifestation of the case in the article is skin rash and exudation of external auditory canal, followed by head mass and abnormal hepatic enzyme. Due to the displayed non-specificity, eczema and head cyst were misdiagnosed. Eventually, LCH was diagnosed by autopsy and immunohistochemical examination. If the patients with superficial masses, repeated skin rash, refractory otitis media, long-term irregular fever and enlarged lymph nodes of liver and spleen without specific reasons were observed clinically, LCH should be considered, and autopsy and immunohistochemical examination should be performed in a timely manner, so as to avoid misdiagnosis or missed diagnosis.