中西医结合治疗小儿反复呼吸道感染45例临床观察

Clinical observation of 45 cases of children with repeated respiratory tract infection by combined traditional Chinese medicine and Western medicine

目的观察中西医结合治疗小儿反复呼吸道感染的临床疗效。方法将90例反复呼吸道感染患儿随机分为治疗组和对照组,各45例。对照组给予卡介苗和葡萄糖酸锌口服液,治疗组在对照组治疗方法的基础上口服黄芪防风汤,并随症加减。2组均连续治疗2月并随访1年后统计疗效。结果治疗组总有效率为88.89%,对照组为68.89%,2组总有效率经统计学分析,差异均有统计意义(P<0.05);2组治疗前血清免疫球蛋白、T淋巴细胞亚群经统计学分析,差异无统计意义(P>0.05);治疗后2组免疫指标较治疗前均显著升高,组间比较差异有统计意义(P<0.05),且治疗组升高幅度大于对照组(P<0.05);治疗组不良反应发生率为15.56%,对照组为11.11%,2组不良反应发生率经统计学分析,差异无统计意义(P>0.05)。结论中西医结合治疗小儿反复呼吸道感染疗效确切,能显著提高机体免疫力,且不良反应小,值得在临床上推广应用。

Objective To observe the clinical efficacy of 45 cases of children with repeated respiratory tract infection by combined traditional Chinese medicine and Western medicine. Methods 90 cases of children with repeated respiratory tract infection were randomized into control group and treatment group with 45 cases in each.The control group was given BCG vaccine and Zinc Gluconate Oral Liquid. On the basis of control group therapy,the treatment group was treated by oral Huangqi Fangfeng Tang modified according to symptoms.Children in two groups were continuous treatment for 2 months,and the clinical efficacy will be observed and concluded after one year of follow-up.Results The total effective rate was 88. 89% in the treatment group,68. 89% in the control group,the difference in two groups was statistically significant（ P〈0.05）; before treatment,statistic analysis showed that there was no significant difference of children＇s serum immunoglobulin and T lymphocytes subset in two groups. After treatment,the immune indexes were significantly improved than before,differences between two groups were statistically significant（ P〈0.05）.But the immune index of the treatment group improved more than it of the control group（ P〈0.05）; the adverse reaction incidence was 15.56% in the treatment group,11.11% in the control group,statistic analysis showed that there was no significant difference of adverse reactions in two groups（ P〈0.05）.Conclusion Children with repeated respiratory tract infection can be treated by combined treatment of traditional Chinese medicine and Western medicine with little adverse reaction and improved immunity of the organism,which is worthy of clinical promotion.