鼠神经生长因子联合穴位注射治疗特发性面神经麻痹临床疗效分析

Effects of Nerve Growth Factor Combined with Acupoint Injection on patients with Idiopathic Facial Paralysis

目的:探讨鼠神经生长因子联合穴位注射治疗特发性面神经麻痹的疗效。方法:特发性面神经麻痹患者60例随机分成对照组和治疗组,各30例。2组均使用维生素B1、B12,氢溴酸加兰他敏混合注射液进行穴位注射;在此基础上,治疗组给予鼠神经生长因子肌肉注射。分别在治疗前、后进行面神经功能评价及临床疗效评估。结果:治疗前,2组的面神经功能评分差异无统计学意义(P>0.05)。治疗后24 d,对照组和治疗组的面神经功能评分分别为(40.50±2.01)分和(46.20±1.52)分,均较治疗前明显改善(P<0.05),且治疗组评分低于对照组(P<0.05)。治疗后24 d,对照组和治疗组的总有效率分别为76.67%和93.33%,治疗组有效率高于对照组(P<0.05)。结论:鼠神经生长因子联合穴位注射治疗特发性面神经麻痹疗效优于单一穴位注射。

Objective： To investigate the effects of nerve growth factor （NGF） combined with acupoint injection on patients with idiopathic facial paralysis. Methods： Sixty patients with idiopathic facial paralysis were randomly divided into control group and treatment group （n=30 each）. All the cases in two groups were treated with acupoint injection of vitamin B1, vitamin B12, and galanthamine hydrobromide. The cases in the treatment group were given additional mouse NGF intramuscular injection. The Facial nerve function and clinical efficacy were evaluated. Results： The scores of facial nerve function of the two groups were comparable before treatment （P〉0.05）. The scores of facial nerve function of the two groups were significantly higher after the treatment and the score in the treatment group was higher than that in the control group, （40.50±2.01） vs. （46.20±1.52） （P〈0.05）. The total efficiency of the treatment group was 93.33%, which was significantly higher than that of the control group （76.67%） （P〈0.05）. Conclusion： The effect of NGF combined with acupoint injection for treating patients with idiopathic facial paralysis is better than the single point injection.