摘要
目的 探讨糖化血红蛋白水平与冠脉病变SYNTAX积分的关系及意义。方法 回顾性分析167例行冠脉造影的急性冠脉综合征患者资料,抽取空腹血清用高效液相色谱法测定Hb A1c水平。采用SYNTAX积分评估冠脉病变程度,分为三组：低危组、中危组、高危组,比较各组间Hb A1c水平及其他临床资料。结果 按照SYNTAX积分不同所分的三个组中,经过字2检验,发现Hb A1c以及年龄差异存在统计学意义（P〈0.05）。经多元逐步分析及Logistcs回归分析,只有SYNTAX积分与Hb A1c的差异具有统计学意义（P〈0.05）,表明变量中只有Hb A1c与SYNTAX积分具有相关性。Hb A1c的OR范围为（1.022～1.778）,说明Hb A1c与SYNTAX积分呈正相关。结论 Hb A1c水平与SYNTAX积分正相关,可以预测冠脉狭窄病变的严重程度。
Objective To analyze the correlation between glycated hmoglobin （HbAlc） and severity of coronary artery lesions evaluated by SYNTAX score, Methods One hundred and sixty-seven patients who underwent percutaneous coronary intervention after identified acute coronary symptoms were enrolled and retrospectively studied. The serum HbAlc levels of the patients were tested by high-performance liquid chromatography. The patients were divided into low risk group, middle risk group and high risk group according to the degree of coronary lesions evaluated by SYNTAX integral. And the HbAlc levels and other clinical data among the three groups were compared. Results The level of HbAlc was different in the three groups. Multivariate stepwise regression showed that there was independent correlation between HbAlc and SYNTAX integral （P〈0.05）. Correlation analysis showed that the correlation between the level of HbAlc and SYNTAX integral was significant （95%CI： 1.022-1.778）. Conclusion The level of HbAlc is apt to reflect the severity of coronary artery lesions and could predict SYNTAX integral in patients with coronary stenosis.
出处
《临床医学研究与实践》
2016年第19期1-3,共3页
Clinical Research and Practice
基金
国家自然科学基金(No.81500308)
