罗哌卡因联合芬太尼对自控硬膜外无痛分娩效果观察

Clinical research of ropivacaine combined with fentanyl for patient-controlled epidural analgesia delivery

目的观察新的局麻药罗哌卡因联合芬太尼用于自控硬膜外分娩的镇痛效果,并总结应用体会。方法对120例单胎头位足月产妇、无产科合并症的初产妇施行罗哌卡因联合芬太尼自控硬膜外无痛分娩镇痛法(观察组),并选取120例同期同条件的产妇作为对照组。采用视觉摸拟评分法(VAS法)评价镇痛效果,并观察两组镇痛效果、产程时间、产后出血量及新生儿情况。结果观察组的无痛分娩效果优于对照组,两组新生儿阿氏评分及产妇产后出血量比较,差异无统计学意义(P>0.05)。结论罗哌卡因联合芬太尼自控硬膜外分娩镇痛法用于无痛分娩,镇痛效果确切,可减少出血量,且对母婴无不良影响。

Objective To observe the anesthetic effect of ropivacaine combined with fentanyl for patient-controlled epidural analgesia delivery, and summarize the clinical experience. Methods One hundred and twenty cases of puerperal with full-term birth, monocyesis and without obstetric complications who underwent ropivacaine card combined with fentanyl patient-controlled epidural analgesia were selected as observation group, and 120 cases of puerperal with the same conditions but without epidural analgesia were selected as the control group. Visual analogue score （VAS） was carried out to evaluate the analgesic efficacy of the two groups. And the labor time, amount of postpartum hemorrhage, postpartum hemorrhage and neonatal situations of the two groups were compared. Results The analgesic efficacy in the observation group was superior to that of control group. The neonatal Apgar score and the amount of postpartum hemorrhage between these two groups had no significant difference （P〉0.05）. Conclusion The analgesic efficacy of ropivacaine combined with fentanyl for patient-controlled epidural analgesia delivery is obvious. It can reduce the rate of cesarean section, and have no adverse effects on mothers and infants.