400例急性胰腺炎患者抗菌药物应用分析

Analysis on Application of Antibiotics in 400 Cases of Acute Pancreatitis

目的:了解四川省人民医院温江院区(以下简称"我院")急性胰腺炎(acute pancreatitis,AP)患者抗菌药物应用现状,为实际临床工作中的合理性用药提供一些参考。方法:对2014年1月至2015年12月我院400例AP患者抗菌药物使用情况进行分析。结果:AP患者中使用频次最多的为头孢菌素类抗菌药物,占44.15%(328/743);使用频次数居前10位的药品中,奥硝唑占29.61%(220/743),应用最多;联合用药治疗中,两种药物联合应用者较多;310例(77.50%)患者存在无指征预防性使用抗菌药物。结论:AP患者抗菌药物不合理应用较为普遍,应加强对抗菌药物的管理,促进临床合理用药。

To investigate the application status of antibiotics in acute pancreatitis （ AP ） in Sichuan Provincial People＇s Hospital of Wenjiang Branch （ hereinafter referred to as “our hospital”） , so as to provide reference for the rational application of drugs in clinic.METHODS： Analysis was conducted on the application of antibiotics in 400 cases of AP from Jan.2014 to Dec.2015.RESULTS： Cephalosporins antibiotics ranked by frequency of usage took the lead, accounting for 44.15%（ 328/743 ） .Of the top 10 antibiotics ranked by frequency of usage, ornidazole dominated the first place, accounting for 29.61%（ 220/743 ） . Of the drug combination treatment, two-drug combination took the lead.And 310 cases（77.50%） had administration of non-infected indications.CONCLUSIONS：The irrational application of antibiotics in AP patients was common, it is necessary to strengthen the management on antibiotics and promote the rational application of drugs in clinic.