金黄色葡萄球菌性烫伤样皮肤综合征220例临床及药敏分析

The Clinical and Drug Sensitivity Analysis of 220 Cases of Staphylococcal Scalded Skin Syndrome

目的:总结金黄色葡萄球菌性烫伤样皮肤综合征发病的影响因素、临床表现和治疗。方法:回顾性分析220例金黄色葡萄球菌性烫伤样皮肤综合征患儿临床资料。结果:3岁以下儿童为好发人群,39例患儿发病前有明显诱因,178例临床标本培养,有12例培养出金黄色葡萄球菌,220例患者经抗生素治疗均痊愈。结论:金黄色葡萄球菌性烫伤样皮肤综合征好发于3岁以下儿童,大部分病例无法找到明确诱因,细菌培养阳性率低,一代、二代头孢类抗生素疗效好。

Objective： To investigate the influencing factors,clinical manifestations,and therapy of staphylococcal scalded skin syndrome. Methods： Retrospective analysis of the clinical data of 220 cases of staphylococcal scalded skin syndrome in children from January of 2013 to November 2015. Results： The children under the age of 3 are the vulnerable population. The definite causes of the disease can be found in 39 cases,and we successfully cultured 12 clinical strains of Staphylococcus aureus from 178 clinical specimens. Antibiotics successfully cured all the patients. Conclusion： The children under the age of 3 are the vulnerable population of staphylococcal scalded skin syndrome,and the definite causes could not be identified in most of the cases. The positive rates of the bacteria culture of the clinical species were low,and the first and second generation of cephalosporins have good treatment effects on the disease.