作为药物释放载体的电纺超细纤维

A Review, Fabrication of Drug-loaded Electrospun Fibers for Controlled Release

静电纺丝纤维具有高的比表面积和类似于天然细胞外基质的纳米尺度结构,使得其在药物释放及组织工程方面显示出很大的应用潜力。对电纺丝技术的原理和特点,载药电纺纤维的制备方法及其在创伤敷料、术后防粘连、抗癌中的应用做一综述。

Due to the large specific surface area and the similarity to the extracellular matrix, the electrospun fibers shows great potential in the applications of drug controlled release and tissue engineering. This review paper focuses on clarifying the fundamental principle of the electrospinning technique, and summarizing the fabrication approaches of the drug-loaded electrospun fibers along with its biomedical applications.