高效液相色谱法分析23%松脂酸铜水乳剂

Analysis of Songzhisuantong 23% EW by HPLC

建立了松脂酸铜高效液相色谱分析方法。样品与氢氧化钠和四氢呋喃反应,以盐酸酸化,乙酸乙酯萃取蒸干,甲醇定容后,进行液相色谱检测。结果表明,该方法在1-200 mg/L范围内,线性关系良好,相关系数为0.996 1。加标回收试验的平均回收率为93.40%,变异系数为3.17%。该方法操作便捷、准确,适用于松脂酸铜制剂及水中常量松脂酸铜的定性定量分析。

A HPLC method was established for determination of songzhisuantong 23% EW.The sample reacted with sodium hydroxide,then reaction mixture was acidized with hydrochloric acid,extracted with ethyl acetate,analyzed by HPLC.The results showed that at the concentration of 1-200 mg/L,the correlation coefficient was 0.996 1.The average recovery of the method was 93.40%,and the relative standard deviation was 3.17%.The method was simple,and the precision and accuracy were high.