精神分裂症患者合并糖尿病对认知功能的影响分析

The Effect of Diabetes Mellitus on Cognitive Function in Schizophrenia Patients

目的分析精神分裂症患者合并糖尿病对认知功能的影响。方法研究对象选取该院2015年1—12月收治的65例合并有糖尿病的精神分裂症患者,将其纳入研究组的范畴;随机选择同期治疗的65例未合并糖尿病及其他躯体疾病的精神分裂症患者作为对照组。采用阳性和阴性症状量表(PANSS)、精神分裂症认知功能量表(MCCB)对患者进行评价。结果研究组和对照组患者的PANSS评分差异无统计学意义(P>0.05);研究组患者MCCB中的语义流畅、符号编码、数字序列等指标均优于对照组,对比差异有统计学意义(P<0.05)。结论精神分裂症患者合并糖尿病的患者对比无合并症的患者认知功能损害更为严重,临床中应重视对两种疾病的治疗。

Objective To analyze the schizophrenic patients with diabetes on cognitive function. Methods The subjects selected in our hospital from January 2015 to December 2015 were treated 65 cases of diabetes associated with schizophrenia, which is included in the scope of the study group; 65 randomly selected patients without treatment over the same period diabetes and other physical schizophrenia disease as a control group. Positive and Negative Syndrome Scale （ PANSS）, schizophrenia, cognitive function scale （ MCCB） patients were evaluated. Results The study group and the control group of patients PANSS score difference is small, not statistically significant （ P〉 0.05）; MCCB patients in the study group of semantic fluency, symbol coding sequence of numbers and other indicators are better than the control group, comparing differences in the results statistically significant （P 〈0.05）. Conclusion Patients with schizophrenia and diabetes without compli-cations contrast cognitive impairment in patients with more severe clinical disease should pay attention to two kinds of treatment.