阿托伐他汀治疗老年急性心肌梗死患者的疗效及对血脂水平的影响

Atorvastatin on Acute Myocardial Infarction in Elderly and Its Effect on Blood Lipid Levels

目的为有效恢复急性心肌梗死心功能,探究药物阿托伐他汀用于临床疾病治疗的可行性。方法方便选取2015年3月—2016年4月期间该院门诊部收治的急性心肌梗死老年患者70例,按病床单双号分为两组包括治疗组35例、单一组35例。单一组给予降脂、溶栓等治疗,治疗组在此基础上加用阿托伐他汀,观察治疗前后心电图变化情况、血脂水平变化情况。结果未治疗时两组心电图指标IVST、LVDD、LVMI变化比较差异无统计学意义,P>0.05,治疗后治疗组较单一组IVST、LVMI、LVDD改善效果好,P<0.05;入院时两组患者血清血脂指标甘油三酯、胆固醇、HDLC、LDL-C比较差异无统计学意义,P>0.05,用药后治疗组较单一组甘油三酯、胆固醇、LDL-C水平低,P<0.05,两组HDL-C水平改善比较差异无统计学意义,P>0.05。结论急性心肌梗死患者治疗时,为快速恢复梗死区血供、疏通血栓血管,降低疾病致死、致残率,临床可使用阿托伐他汀能提高治疗效果,缓解患者症状。

Objective To effectively restore cardiac function in patients with acute myocardial infarction, explore the drug atorvastatin for clinical treatment of diseases of the feasibility. Methods Convenient selection in our hospital outpatient department admitted from March 2015 to Apirl 2016 period in elderly patients with acute myocardial infarction, 70 cases divided into two groups according to odd and even number of beds including the treatment group of 35 patients, a single group of 35 patients. Single group received lipid-lowering, thrombolytic therapy, the treatment group was based on the use of atorvastatin, ECG changes, changes in blood lipid levels before and after treatment. Results Untreated two ECG results indicators IVST, LVDD, LVMI change relatively insignificant difference, P > 0.05, the treatment group than a single group IVST, LVMI, LVDD improving effect, P <0.05; two groups of patients on admission serum lipids indicators triglycerides,cholesterol, HDL-C, LDL-C relatively insignificant difference, P> 0.05, after the drug treatment group than a single group of triglycerides, cholesterol, low LDL-C levels, P <0.05, two HDL-C level to improve the relatively insignificant difference,P> 0.05. Conclusion Patients with acute myocardial infarction, infarct region for the rapid restoration of blood supply, blood clots and clear the blood vessels, reducing disease mortality, morbidity, the clinical use of atorvastatin may be able to improve the therapeutic effect, relieve symptoms.