老年高脂血症患者血脂水平与营养状况相关性探讨

Relationships between blood lipid levels and nutritional status in elderly patients with hyperlipidemia

目的探讨老年高脂血症患者血脂水平与营养状况的相关性。方法将96例老年高脂血症患者作为试验组,另选取同年龄段健康志愿者100例作为对照组,分别对两组血脂水平和营养状况相关指标进行检测并对比结果,采用Pearson线性相关方法确定血脂水平和营养状况相关性。结果试验组三酰甘油(TG)、血清总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)水平均显著高于对照组(P<0.05),而高密度脂蛋白胆固醇(HDL-C)水平比较前者远远低于后者(P<0.05);两组血清钙水平差异无统计学意义(P>0.05),且试验组TP水平远高于对照组(P<0.05);维生素A(Vit A)、维生素B1(Vit B1)、维生素B2(Vit B2)、维生素C(Vit C)、镁和锌水平均远低于对照组(P<0.05);Vit A、Vit B1与HDL-C、TC、TG,HDL-C与镁、锌存在明显正向相关性(r>0,P<0.05),TC、TG、LDL-C与镁、锌均存在明显负向相关性(r<0,P<0.05)。结论老年高脂血症患者血脂水平和营养状况存在明显相关性,维生素和微量元素缺乏可导致脂质沉积、使得血脂水平升高。

Objective To explore the relationships between blood lipid levels and nutritional status in elderlypatients with hyperlipidemia. Methods Ninety-six cases of elderly patients with hyperlipidemia were selected as the experimental group,and another one hundred cases of healthy volunteers with the same age were selected as the control group. The blood lipid levels and nutritional status of two groups were measured and compared,and the relationships between blood lipid levels and nutritional status were analyzed by Pearson linear correlation. Results The levels of TG, TC and LDL-C in the experimental group were significantly higher than those in the control group （ P 〈 0. 05 ） , but the level of HDL-C was lower than that of the latter （P 〈0. 05）. There was no significant difference in the levels of serum calcium between two groups （ P 〉 0. 05 ） . The levels of VitA, VitBl, VitB2, VitC, magnesium and zinc of experimental group were far lower than those in the control group. The levels of VitA,VitBl were significantly related to the levels of HDL-C, TC,TG the level of HDL-C was significantly related to the levels of magnesium and zinc （ r 〉0,P 〈0. 05 ）, while the negative correlation between the levels of TC,TG and LDL-C and the levels of magnesium and zinc （r 〈0, P 〈 0. 05） . Conclusion There is a great interdependency between blood lipid levels and nutritional status in elderly patients with hyperlipidemia, and the lack of vitamins and trace elements can lead to lipid deposition and elevated blood lipids.