摘要
陈皮Citri Reticulatae Pericarpium为芸香科植物橘Citrus reticulata及其栽培变种的干燥成熟果皮,作为一种常用中药,分布广泛,资源丰富,药用价值高。陈皮的主要有效成分为黄酮类化合物,流行病学调查显示橘类黄酮的摄入可改善心脑血管疾病,大量的体内外研究也发现陈皮及其成分具有良好的改善心脑血管疾病的作用,包括调血脂、防治脂肪肝、抗血栓、抗动脉粥样硬化、心脑保护等,以及与之密切相关的抗氧化和抗炎作用等,从而达到预防和治疗心脑血管疾病的功效。
Citri Reticulatae Pericarpium is a common Chinese materia medica, with extensive distribution, abundant resource, and high medicinal value. Epidemiologic studies showed that Citrus flavonoid intake can relieve the symptom of cardiovascular and cerebrovascular disease. Numerous in vitro and in vivo studies have found that Citri Reticulatae Pericarpium and its composition were good to treat cardiovascular and cerebrovascular disease, including hypolipidemic, anti-fatty liver, anti-thrombusis, anti-atherosclerosis, cardio-cerebral-vascular protection, and anti-oxidant and anti-inflammatory effects closely related to the above. Evidence obtained from these studies indicates that Citri Reticulatae Pericarpium has the potential in the prevention and treatment of cardiovascular and cerebrovascular disease.
出处
《中草药》
CAS
CSCD
北大核心
2016年第17期3127-3132,共6页
Chinese Traditional and Herbal Drugs
基金
国家"十二五"科技重大项目(2014ZX09301-307-13)
浙江中医药大学校级重点项目(2015ZZ12)
浙江省重点实验室(2012E10002)
国家中管局"中药药理学"重点学科
关键词
陈皮
心脑血管疾病
二氢黄酮
多甲氧基黄酮
脂肪肝
调血脂
抗动脉粥样硬化
心脑保护
Citri Reticulatae Pericarpium
cardiovascular and cerebrovascular disease
flavonone
polymethoxylated flavones
fatty liver
hypolipidemia
anti-atherosclerosis
cardio-cerebral-vascular protection
