Logistic分析SLE伴消化系统受累的危险因素

Risk factors for digestive system involvement in systemic lupus erythematosus

目的探讨系统性红斑狼疮(systemic lupus erythematosus,SLE)合并消化系统受累的危险因素,为预防该病提供参考.方法采取回顾性方法对医院2013-06/2015-12的130例SLE患者的临床资料进行分析,分析SLE合并消化系统受累的临床资料差异性,并应用Logistic分析其危险因素.结果 130例SLE患者中42例患者伴消化系统受累,比例为32.3%.SLE合并消化系统受累患者中呼吸系统受累、SLE疾病活动指数(SLE disease activity index,SLEDAI)评分的比例差异有统计学意义(P<0.05);呼吸系统受累、SLEDAI评分≥12分均是SLE合并消化系统受累的危险因素(OR均>1.0,且均P<0.05).结论 SLE合并消化系统受累的影响因素较多,而呼吸系统受累、SLEDAI评分均是其影响的危险因素,临床中应引起足够的重视.

AIM To investigate the risk factors for digestive system involvement in systemic lupus erythematosus（SLE） in order to provide reference for the prevention of this disease.METHODS Clinical data for 130 patients with SLE treated from June 2013 to December 2015 were retrospectively analyzed to identify risk factors for digestive system involvement using Logistic regression analysis.RESULTS Of 130 patients with SLE,42（32.3%） had digestive system involvement.Respiratory system involvement and SLE disease activity index（SLEDAI） score 12 points were identified as risk factors for digestive system involvement in SLE（OR 1.0 and P 0.05）.CONCLUSION Respiratory system involvement and SLEDAI score are risk factors for digestive system involvement in SLE.