一种高分子紫外光吸收剂的合成研究

Synthesis of a Maromolecule Benzothriazole Ultraviolet Absorbent

以2-(2-羟基-5-甲基苯基)苯并三唑、聚缩醛和哌嗪为原料,在乙二醇二甲醚溶剂中,经Mannich反应合成1,4-二[2-(2-羟基-5-甲基苯基)苯并三氮唑]哌嗪,确定了较佳缩合工艺条件。考察了物料配比、反应温度和时间对反应收率的影响,并经过正交实验,确定了反应的最佳工艺条件:在乙二醇二甲醚溶剂中,反应温度95℃,反应时间为24 h,n(2-(2-羟基-5-甲基苯基)苯并三唑)/n(HCHO)/n(哌嗪)=1.0∶1.5∶0.7,产品收率为82%,纯度>98%(HPLC面积归一化法)。产品结构经IR、MS和1H-NMR表征。

In ethylene glycol dimethyl ether solvents, With 2-（2-Hydroxy-5-methylphenyl）benzotriazole, piperazine and paraformaldehyde as raw materials, have a synthesis of 1,4-2[2-（2-hydroxy-5-methyl phenyl） benzene and three azole nitrogen] piperazine by the Mannich reaction, a better condensation process conditions were determined.Inspected the material ratio, reaction temperature and influencing of time on the yield of reaction, the optimum reaction conditions were determined by the orthogonal experiment： In ethylene glycol dimethyl ether solvents, reaction temperature 95 ~C, the reaction time of 24 h, n （uv-P）/n （experiment）/n （piperazine）= 1.0 ： 1.5 ： 0.7, the product yield was 82%, the purity was 98% （by HPLC area normalization method）. Product structure was characterized by IR, MS and ^1H-NMR.