有益菌在老年人社区获得性肺炎治疗中的应用

PROBIOTICS:FOR SENIORS WITH COMMUNITY-ACQUIRED PNEUMONIA

目的探讨有益菌在老年人社区获得性肺炎治疗中的作用。方法年龄〉60岁的社区获得性肺炎病人191例,随机分为常规治疗组（A组,68例）、常规药物治疗加用双歧三联活菌胶囊组（B组,61例）、常规药物治疗加用复方嗜乳酸杆菌片组（C组,62例）,比较3组病人抗生素相关性腹泻的发生率、相关不良反应发生率。结果B组、C组抗生素相关性腹泻的发生率及不良反应发生率均明显低于A组,差异有显著性（χ~2=6.372、10.325,P〈0.05）,B组与C组比较差异无显著性（P〉0.05）。结论有益菌用于老年人社区获得性肺炎治疗具有积极作用,可明显减少老年病人抗生素相关性腹泻的发生率及治疗过程中出现的消化道不良反应。

Objective To discuss the effect of probiotics on the aged with community-acquired pneumonia （CAP）. Methods This study consisted of 191 senior patients--agC〉60 years old--with CAP, and randomized to group A （n =68, conventional therapy） ,group B （n = 61, conventional medicine plus Bifid Triple Viable Capsules） and group C （n = 62, conventional medicine plus compound lactobacillus tablets）. The incidence of antibiotic-associated diarrhea and related adverse reactions were com pared between the three groups. Results The incidence of antibiotic-associated diarrhea and related adverse reactions in groups B and C were lower than that in group A （X^2 = 6.372,10.325;P〈0.05）, and the difference in that between groups B and C was not significant （P〉0.05）. Conclusion Beneficial bacteria has an active work on the aged with community-acquired pneumonia, which can reduce the incidence of antibiotic-associated diarrhea and gastrointestinal adverse reactions during the treatment.