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Modeling of microbial growth bioprocesses: Equilibria and stability analysis 被引量:1

Modeling of microbial growth bioprocesses: Equilibria and stability analysis
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摘要 The paper addresses the analysis of nonlinear dynamical models of some microbial growth processes. Equilibrium points, stability analysis, and structural properties are studied for different bioprocesses with various kinetics structures. First, a simple micro- organism growth process on a single limiting substrate is widely analyzed. Second, a microbial growth process combined with an enzyme-catalyzed reaction is investigated. The analysis shows that these kinds of bioprocesses have multiple equilibria, stable or unstable, operational or non-operational. The partition of nonlinear model in linear and nonlinear parts via some structural properties leads to kinetic decoupling and facilitates the equilibria and stability analysis. The performed research is useful for model reduction and for the design of observers and control algorithms. To illustrate the study results, several numerical simulations are provided.
出处 《International Journal of Biomathematics》 2016年第5期37-57,共21页 生物数学学报(英文版)
关键词 Biotechnological processes nonlinear systems modeling stability analysis 微生物生长 稳定性分析 平衡点 非线性动力学模型 过程建模 生长过程 动力学结构 酶催化反应
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