青岛地区甲状腺结节发生率现状调查

Current situation investigation of thyroid nodule incidence rate in Qingdao area

目的：了解青岛地区人群甲状腺结节的发生率、影响因素和流行病学特点。方法：选取在我院健康查体中心登记体检的健康成人，共1718例的查体资料为研究对象，统计分析甲状腺彩色超声检查和甲状腺功能测定结果。结果：研究对象的甲状腺结节检出率为46.92%，其中男性和女性的检出率分别为37.42%、58.55%。女性发生率高于男性，差异有统计学意义（＜0.01）；随着年龄的增长，男女结节的发生率都呈显著升高趋势；有甲状腺结节的人群中血清TPO- Ab、TG- Ab阳性率都明显大于正常人群，差异有统计学意义（＜0.01）。结论：高TPO- Ab、高TG- Ab与甲状腺结节的发生密切相关；青岛地区人群甲状腺结节的发生率较高，应引起我们的高度重视。有甲状腺结节的人群应注意随访，结节易发人群要定期进行健康体检，做到早发现早治疗。

Objective： To investigate the prevalence of thyroid nodules, influence factors and epidemiological characteristics in Qingdao.Methods： 1718 healthy adults＇physical examination data which is registered in our hospital＇s healthy physical examination center was selected as the research object to analysis the color ultrasound examination and thyroid function determination results . Results： The research object of thyroid nodule＇s detection rate is 6.92%, the rate of male and female are 37.42% and 58.55%respectively. Female prevalence is higher than male, the difference was statistically significant （ 〈0.01）;As the growth of the age, both men and women showed a trend of increased significantly about the prevalence of nodules; Thyroid nodules in patients with serum TPO- Ab and TG- Ab positive rate were significantly greater than the general population, the difference was statistically significant （ 〈0.01）Conclusion： High titer of TPO- Ab and TG- Ab may associate with the occurrence of nodules; The prevalence of thyroid nodules in Qingdao showed higher than surrounding areas, and we should pay more attentions. Patients with thyroid nodules should have follow- up examinations at regular intervals. The crowds who are susceptible to the nodules should do periodic health examination, in order to achieve early found and early treatment.