地塞米松在股神经阻滞中应用效果的观察

Observation of application effect by dexamethasone in femoral nerve block

目的观察并评估地塞米松在股神经阻滞中应用的效果及安全性。方法 40例择期行下肢手术患者,随机分为S组和C组,各20例。采用神经刺激器定位进行股神经阻滞,S组给予罗哌卡因和地塞米松,C组给予罗哌卡因,对两组的镇痛效果进行比较。结果 S组感觉阻滞、运动阻滞起效时间[(4.3±1.8)、(6.0±1.8)min]均短于C组[(6.5±1.0)、(7.0±0.6)min](P<0.05),感觉阻滞、运动阻滞持续时间长于C组(P<0.05)。两组均未出现恶心、呕吐、头晕等不良反应。结论罗哌卡因中加入地塞米松用于股神经阻滞能够缩短股神经阻滞的起效时间,延长局部麻醉(局麻)药物的作用时间,效果明显,值得推广。

Objective To observe and evaluate effect and safety of dexamethasone applied in femoral nerve block. Methods A total of 40 patients receiving lower limb surgery were randomly divided into group S and group C, with 20 cases in each group. Both groups received femoral nerve block with nerve stimulator positioning. Group S received ropivacaine and dexamethasone, and group C received ropivacaine alone. Analgesic effects were compared between the two groups. Results Group S had all shorter onset time of feeling and motor block [（4.3±1.8）,（6.0±1.8） min] than group C [（6.5±1.0）,（7.0±0.6） min]（P〈0.05）. Group S also had longer duration of feeling and motor block than group C（P〈0.05）. There were no adverse reactions of nausea, emesis and dizziness in the two groups. Conclusion Combination of ropivacaine and dexamethasone can shorten onset time of femoral nerve block and prolong action time of local anaesthesia drug, along with precise effect. This method is worth promoting.