广州市白云区≤5岁组儿童手足口病发病危险因素的配对病例对照研究

Paired case-control study of risk factors for hand-food-mouth disease among children under 5 years old in Baiyun District of Guangzhou

目的探讨广州市白云区≤5岁组儿童手足口病发病危险因素,为预防控制该人群手足口病提供依据。方法选取2015年广州市白云区185例≤5岁组儿童手足口病病例进行1∶1配对,配对因素为性别、年龄和居住地,对其发病危险因素进行分析。结果单因素分析显示,流动人口(OR=8.2)、职业(OR=6.1)、居住楼层(OR=2.8)、近一周医院就诊史(OR=5.0)、洗手习惯(OR=8.0)、家长手足口病知识掌握程度(OR=5.5)及与其他儿童共用玩具(OR=3.0),与5岁以下儿童手足口病的发病相关。多因素Logistic分析则显示,流动儿童(OR=2.4)、职业(OR=4.7)、近一周医院就诊史(OR=6.1)、洗手习惯(OR=2.7)、家长手足口病知识掌握程度(OR=7.2),与5岁以下儿童手足口病发病密切相关。结论广州市白云区≤5岁组儿童手足口病发病受多种因素影响,院感控制,幼儿良好的环境卫生、个人卫生及提高家长的卫生意识是预防控制手足口病的关键因素。

Objective To explore the risk factors of hand-food-mouth disease in children under 5 years old,in order to provide basis for the prevention and control of hand-food-mouth disease in this group.Methods Totally 185 cases and 185 controls were selected from Baiyun District of Guangzhou during 2015 by the method of 1 ∶ 1 matched case-control study.The matched factors were gender,age and location.The other factors were analyzed.Results Single factor analysis showed that the incidence of hand-foot-mouth disease was related to flowed children（OR = 8.2） occupation（OR = 6.1）,resident floor（OR = 2.8）,medical history in one week before incidence（OR = 5.0）,habit of washing hand（OR = 6.0）,the parents＇ knowledge about hand-food-mouth disease（OR = 5.5） and using toys with other children（OR = 3.0）.Multiple factor logistic analysis showed that the incidence was significantly associated with flowed children（OR = 2.4） occupation（OR = 4.7）,medical history in one week before incidence（OR = 6.1）,habit of washing hand（OR = 2.7） the parents＇ knowledge about hand-food-mouth disease（OR = 7.2）.Conclusion The incidence of hand-foot-mouth disease among children under5 years old in Baiyun District was related to various factors.It is important method for the prevention of hand-food-mouth disease that providing good environment and personal sanitation and improving health consideration of parents.