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Gasdermins pore cell membrane to pyroptosis 被引量:9

Gasdermins pore cell membrane to pyroptosis
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摘要 Cell death programmes including apoptosis, pyroptosis, autophagy, oncosis and necroptosis were defined dependent on distinct biochemical mechanism and genetic pathways. Pyroptosis is an inflammatory form of programmed cell death characterized by the activation of inflammatory caspases, cell swelling, pore formation on plasma mem- brane and rapid cellular rupture which cause the release of cell contents followed by robust inflammatory responses (Cookson and Brennan, 2001; Jorgensen and Miao, 2015). Cell death programmes including apoptosis,pyroptosis,autophagy,oncosis and necroptosis were defined dependent on distinct biochemical mechanism and genetic pathways.Pyroptosis is an inflammatory form of programmed cell death characterized by the activation of
出处 《Science China(Life Sciences)》 SCIE CAS CSCD 2016年第10期1090-1092,共3页 中国科学(生命科学英文版)
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