中药内服外用合治寒湿瘀滞型复发性外阴阴道假丝酵母菌病的临床研究

Clinical Research of Internal Traditional Chinese Medicine in Treating Cold Dampness Stasis Type of Recurrent Vulvovaginal Candidiasis

目的：探讨中药内服外用合治寒湿瘀滞型复发性外阴阴道假丝酵母菌病的临床疗效及对阴道微生态的影响。方法：选择2014年8月～2015年10月间来我院就诊的RVVC患者100例作为研究对象，随机分成2组，西药组和中药组，每组50例。西药组给予硝基咪康唑塞阴道治疗；中药组给予中药口服＋外治联合应用治疗。观察2组患者3个疗程后的治愈率、临床治愈时阴道微生态失衡率、临床治愈后3个月内的复发率等指标。结果：2组患者3个疗程后的治愈率分别为90．00％、88．00％，2组比较无统计学差异（P〈0．05）；2组患者临床治愈时阴道微生态失衡率分别为51．11％、13．64％，2组比较有统计学差异（P〈0．05）；2组患者临床治愈后3个月内的复发率分别为48．89％、11．36％，2组比较有统计学差异（P〈0．05）。结论：中药内服外用合治寒湿瘀滞型复发性外阴阴道假丝酵母菌病疗效显著，复发率低，可明显改善患者的阴道微生态，减少复发。

Objective： The aim of this study was to investigate the herbal internal and external combined the efficacy of treatment of cold dampness stagnation type recurrent vulvovaginal candida mycoderma and the vaginal micro ecological impact. Methods： Selection of RVVC patients in our hospital from October -2015 to August 2014, 100 patients were randomly divided into two groups, 50 cases in each group. The western medicine group was given Zuosai nitro miconazole vaginal treatment; traditional Chinese medicine group was given oral medicine and external treatment combination. The cumulative cure rate of 2 groups of patients after 3 courses of treatment, clinical cure rate of vaginal micro ecological imbalance, 3 months after the cumulative recurrence rate and other indicators. Results： The cumulative cure rates of the two groups were 90.00% and 88.00%, respectively, and there was no significant difference between the two groups（P〈0.05）; Two groups of patients with clinical cure vaginal micro ecological imbalance rate was 51.11%, 13.64%, the two groups were statistically significant difference（P〈0.05）; The cumulative recurrence rate in the two groups was 48.89%, 11.36% after 3 months, and there were significant differences between the two groups（P〈0.05）. Conclusion： Chinese herbs external combined treatment of cold dampness stagnation type recurrent vulvovaginal Candida disease curative effect significantly, the recurrence rate is low, can significantly improve the patient＇ s vagina micro ecological, reduce the recurrence.