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冠状动脉慢性完全闭塞病变成功介入治疗后心功能改善的影响因素 被引量:6

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摘要 目的:探讨冠状动脉慢性完全闭塞病变(CTO)患者介入治疗后心功能改善的影响因素。方法选择成功介入治疗冠状动脉 CTO 患者48例,根据介入治疗后9~12个月心功能变化分为改善组29例和未改善组19例,比较两组年龄,心绞痛病程,吸烟、高血压、糖尿病、血脂异常病史,血糖、血脂、血清 N 端脑钠肽前体(NT-proB-NP)等指标,以及冠脉病变、侧枝循环特点,分析影响介入治疗后心功能改善的因素。结果改善组年龄(48.6±6.1)岁,心绞痛病程(110.7±29.6)周,术前血清 NT-proBNP 水平为(230.20±58.30)pg/mL;未改善组年龄(61.4±10.3)岁,心绞痛病程(110.7±29.6)周,术前血清 NT-proBNP 水平为(403.90±81.10)pg/mL;两组年龄、心绞痛病程、术前血清 NT-proBNP 水平比较差异有统计学意义(P <0.01或<0.05)。心功能改善组侧枝循环评分高于未改善组(P <0.05)。Logistic 回归分析显示,年龄较轻(OR =0.913,95%CI 0.769~0.985,P =0.031,)、心绞痛病程较短(OR =0.938,95%CI 0.893~0.984,P =0.010)是心功能改善的独立正向预测因素。结论年龄及心绞痛病程对冠状动脉 CTO 患者术后心功能改善有显著影响。
出处 《山东医药》 CAS 北大核心 2016年第33期47-49,共3页 Shandong Medical Journal
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