2014年崇明县感染性腹泻病原菌监测结果分析

Analysis of the surveillance results of infectious diarrhea pathogens in Chongming County in 2014

目的了解上海市崇明县2014年感染性腹泻病原菌的分布、流行病学特征和药物敏感情况,为临床合理用药及预防工作提供科学依据。方法对监测医院肠道门诊的感染性腹泻患者按一定的抽样间隔进行调查,并采集患者的肛拭标本进行细菌分离检测,用K-B法对检出的致病菌进行药物敏感试验。结果 2014年监测点医院共监测到腹泻标本108例,检出病原菌株13例,检出率为12.04%。检出的主要致病菌为致泻性大肠埃希菌(46.15%,6/13)、副溶血性弧菌(30.77%,4/13)、沙门菌(15.38%,2/13)、空肠弯曲菌(7.69%,1/13)。药敏试验结果显示,各菌属对抗生素都有不同程度的耐药。结论 2014年崇明县监测医院腹泻患者中的病原菌以致泻性大肠杆菌为主,夏秋季节是细菌感染性腹泻的高发季节,各种病原菌耐药性不同,应加强主动监测。

Objective To understand the distribution,epidemiological features and drug- sensitive conditions of infectious diarrhea pathogens in Chongming county,Shanghai in 2014,so as to provide scientific basis for the rational clinical use of drugs and prevention work. Methods To investigate infectious diarrhea cases in the Enteric Diseases Clinic of monitored hospital according to sampling interval. Anal swabs of the cases were collected for bacteria separation and test,and then drug sensitivity test was carried out by using K- B method on the detected pathogenic bacteria. Results In 2014,the number of diarrhea cases detected in the monitored hospital was 108,and pathogenic strains were detected in 13 cases with the detection rate of 12. 04%.The detected pathogenic bacteria were mainly diarrheogenic Escherichia coli（ 46. 15%,6 /13）, Vibrio parahaemolyticus（ 30. 77%,4 /13）,Salmonella（ 15. 38%,2 /13）,and Campylobacter jejuni（ 7. 69%,1 /13）. According to the results of drug sensitivity tests,each type of bacterium has different levels of resistance against antibiotics. Conclusion In 2014,diarrheagenic Escherichia coli was the main pathogenic bacteria causing diarrhea among patients in monitored hospital in Chongming County. Summer and autumn are high seasons for bacterial diarrhea. Different pathogenic bacterium has different levels of drug resistance,therefore,active surveillance needs to be enhanced.