摘要
缺血再灌注是多种器官系统疾病的重要病理生理过程,而可控性坏死在缺血再灌注损伤中发挥着重要作用。笔者拟就3种可控性坏死相关分子机制及其在缺血再灌注损伤疾病中的作用进行综述如下,旨在为新生儿缺氧缺血性脑病等治疗提供新思路。
Ischemia-reperfusion is a critical pathophysiological progress in many diseases involved in different organisms and systems. Regulated necrosis plays crucial roles in ischemia- reperfusion injury. This paper focuses on 3 types of regulated necrosis and their roles in related ischemia-reperfusion diseases, which may provide a new insight into hypoxic-ischemic encephalopathy of neonatus.
出处
《中华妇幼临床医学杂志（电子版）》
CAS
2016年第5期613-616,共4页
Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition)
基金
国家自然科学基金项目(81330016、81270724、81330016、81501301)
四川省科技厅公益民生项目(2014SZ0149)
四川省科技厅青年科技创新研究团队基金(2016TD0002)~~
关键词
坏死
可控性坏死
缺血
再灌注损伤
细胞凋亡
分子作用机制
Necrosis
Regulated neerosis
Ischemia
Reperfusion injury
Apoptosis
Molecular mechanisms of action
