1Steinbrech DS,Mehrara BJ,Saadeh PB,et al.Hypoxia regulates VEGF expression and cellular proliferation by osteoblasts in vitro.Plast Recornstr Surg,1999,104:738-747.
2Kaigler D,Krebsbach PH,Polverini PJ,et al.Role of vascular endothelial growth factor in bone marrow stromal cell modulation of endothelial cells.Tissue Eng,2003,9:95-103.
3Shweiki D, Itin A, Soffer D, et al. Vascular endothelial growth factor inducesd by hypoxia may mediate hypoxia-initiated angiogenesis[J]. Nature, 1992,359: 843.
4Padro T, Ruiz S, Bieker R, et al. Increased angiogenesis in the bone marrow of patients with acute myeloid leukemia [J]. Blood,2000,95: 2637 -2644.
5Weidner N. Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors[J]. Breast Cancer Res Treat, 1995,36:169-180.
6Aguayo A, Kantarjian H, Manshouri T, et al. Angiogenesis in acute and chronic leukemias and myelodysplastic syndromes [J]. Blood, 2000,96:2240-2245.
7Brunner B, Gunsilius E, Schumacher P, et al. Blood levels of angiogenin and vascular endothelial growth factor are elevated in myelodysplastic syndrome and in actue myeloid leukemia [J].Journal of Heamatotherapy & Stem Cell Research,2002, 11:119-125.
8Dias S, Hattori K, Zhu ZP, et al. Autocrine stimulation of VEGFR-2 activates human leukemic cell growth and migration[J]. J Clin Invest,2000,106:4511 -4521.
9Dias S, Hattori K, Heissig B, et al. Inhibition of both paracrine and autocrine VEGF/VEGFR-2 signaling pathways is essential to induce long-term remission of xenotransplanted human leukemias[J]. Proc Natl Acad Sci ,2001,98:10857-10862.
10Perez-Atayde AR, Sallan SE, Tedrow U, et al. Spectrum of tumor angiogenesis in the bone marrow of children withacute lymphoblastic leukemia[J]. Am J Pathol, 1997,150: 815-821.
