南山藤属植物化学成分及生物活性研究进展

Review on Chemical Constituents and Biological Activities of Dregea E.Mey

萝藦科南山藤属植物广泛分布于亚洲和非洲南部,全株药用,临床应用广泛。化学结构类型包括甾体、苯丙素、寡糖等,其中C21甾体类成分为该属植物中主要化学结构类型,并具有抗肿瘤、抗抑郁、抗炎及免疫调节等作用。本文对南山藤属植物化学成分及生物活性进行综述,以期为更好地开发和利用南山藤属植物资源提供参考。

The plants of Dregea E. Mey belonging to Asclepiadaceae family were widely distributed in Asia and South Africa and had been used in the clinical application as medicinal herbs. The chemical constituents of Dregea E. Mey contain steroids,phenylpropanoids,oligosaccharides,in which steroids derivatives were the main constituents in this genus.Pharmacological studies on these plants had demonstrated anti-tumor,anti-depression,anti-inflammatory and immuneregulatory activities,etc. In this study,the chemical constituents and their biological activities from Dregea E. Mey were reviewed and summarized for its further development and utilization.