《低增生性血小板减少症的血小板输注指南》主要内容解读及启示

Interpretation and inspiration of Guidance on Platelet Transfusion for Patients with Hypoproliferative Thrombocytopenia

《低增生性血小板减少症的血小板输注指南》（以下简称为《指南》）是2009年由来自英国、美国、加拿大、德国、比利时、澳大利亚6个国家的24名输血学专家，为规范该病诊断和治疗而组成的国际化专业组织制定，2015年，该组织专家对其进行更新。笔者从《指南》所涉及的是否需要进行预防性血小板输注、最低血小板阈值、血小板输注剂量、同型输注、RhD阴性患者输注RhD阳性患者血小板的处理方法、是否应该进行血小板交叉配合试验以及全血来源浓缩血小板和机采血小板的疗效比较7个方面对低增生性血小板减少症患者的诊断和治疗进行内容解读，并对国内、外该病的诊疗现状进行对比，以期为我国低增生性血小板减少症的规范治疗提供帮助。《指南》可以为低增生性血小板减少症的临床诊疗提供理论依据。

Guidance on Platelet Transfusion for Patients with Hypoproliferative Thrombocytopenia （hereinafter referred to as the Guide）was created by an international professional organization which composed of 24 national experts in blood transfusion from Britain, the United States, Canada, Germany, Belgium and Australia, in order to standardize the diagnosis and treatment of hypoproliferative thrombocytopenia. They updated it in 2015. The author interpret the content of the Guide in seven respects., the need for prophylactic platelet transfusions, minimum platelet threshold, platelet transfusion dose, transfusion with same blood type,transfusion of RhD negative patients with RhD positive platelet, platelet cross matching test and comparison of the efficacy between apheresis platelets and concentrated plasma. Meanwhile the the status of the diagnosis and treatment of the disease are compared between at home and abroad. The Guide can provide a theoretical basis for clinical diagnosis and treatment of the disease.