前列腺癌老年患者生活质量与主观幸福感的调查研究

Quality of life and subjective well-being in elderly patients with prostate cancer

目的探讨前列腺癌老年患者生活质量与主观幸福感的现状及两者之间的相关性。方法采用问卷调查的方式,按照连续研究对象招募法原则,以200例≥60岁前列腺癌患者为调查对象,在入院时,采用EORTC QLQ-PR55测定量表、幸福感指数量表对患者生活质量与主观幸福感进行调查。结果前列腺癌老年患者的生活质量较差,主观幸福感较低;不同分期的前列腺癌老年患者生活质量不同,且中晚期前列腺癌老年患者生活质量较早期患者低(P<0.05)。主观幸福感与躯体功能、角色功能、认知功能、情绪功能、社会功能及总健康状况呈正相关(r=0.653、0.485、0.573、0.671、0.563、0.836,均P<0.05),与疼痛、失眠、经济困难、泌尿症状及治疗相关症状呈负相关(r=-0.638、-0.565、-0.714、-0.511、-0.604,均P<0.05)。结论前列腺癌老年患者的生活质量、主观幸福感均较低,两者之间存在相关性。

Objective To assess the quality of life and subjective well-being in elderly patients with prostate cancer. Methods Two-hundred prostate cancer patients aged ≥60 were surveyed by questionnaires according to continuous research object recruitment method. The quality of life and subjective well-being of all patients were studied using the EORTC QLQ-PR55 scale and happiness index scale when patients were admitted to hospital. Results Elderly patients with prostate cancer had relatively poor quality of life and subjective well-being. Moderate or advanced stage patients showed even lower quality-of-life scores compared with patients at early stage（ P〈0. 05）. Moreover,their subjective well-being were positively associated with physical function,role function,cognitive function,emotional function,social function and overall health status（ r = 0. 653,0. 485,0. 573,0. 671,0. 563,0. 836,respectively,all P〈0.05）; and negatively associated with pain,insomnia,economic difficulties,urinary symptoms and treatment related symptoms（ r =- 0. 638,- 0. 565,- 0. 714,- 0. 511,- 0. 604,respectively,all P〈0. 05）. Conclusion The quality of life and subjective well-being in elderly patients with prostate cancer are relatively poor,and the quality of life and subjective well-being are closely correlated.