低效价不规则抗体对妇科患者红细胞输注效果的影响

Effect of low titer irregular antibody on the effectiveness of RBC transfusion in gynecological patients

目的研究低效价不规则抗体对妇科患者红细胞输注效果的影响。方法评价2013年1月-2016年6月本院妇科输血患者的红细胞输注效果,用抗球蛋白增强试验检测红细胞无效输注患者血清中低效价不规则抗体,分析低效价不规则抗体阳性患者红细胞输注的临床和实验室相关资料。结果 10%的妇科输血患者(75/748)存在红细胞无效输注,10.7%的红细胞无效输注患者(8/75)低效价不规则抗体阳性,且没有明显迟发性溶血性输血反应。结论低效价不规则抗体是引起妇科患者红细胞无效输注的重要原因,在临床输血过程中应给予足够重视。

Objective To study the relationship between low titer irregular antibody and invalid RBC transfusion cases in gynecologic patients. Methods The effectiveness of RBC transfusion in gynecologic patients was determined by detection of low titer irregular antibody by anti-globulin enhancement test in the serum of gynecologic patients who experienced invalid blood transfusion. The clinical and, laboratory data of gynecologic patients whose low titer irregular antibodies were positive were retrospectively analyzed. Results The proportion of invalid transfusion was 10% （75/748） in all gynecologic patients who had received blood transfusion. The proportion of positive low titer irregular antibody was 10. 7% （8/75） in all gynecologic patients who received invalid blood transfusion, but did not experience significant late-onset hemolytic transfusion reaction. Conclusion Low titer irregular antibody is an important cause of invalid RBC transfusion in gynecologic patients and sufficient attention should be paid to this marker during blood transfusion.