直肠癌低位前切除术后不同肠道重建方式比较的Meta分析

Meta Analysis of Different Intestinal Tract Reconstruction after Low Anterior Resection for Rectal Cancer

目的:分析直肠癌低位前切除术后的不同肠道重建方式对患者术后早期及术后排便功能的影响。方法:采用中英文数据库对1995年12月至2016年5月期间发表的比较不同肠道重建方式疗效的随机对照临床试验进行检索,选取重建成功率、吻合口漏、24h排便频次等指标评价比较。结果:采用两种方式在伤口感染、吻合口漏、术后24h排便频次发生率比较差异无统计学意义(P>0.05);结肠J型小贮袋术的重建失败率高于结肠成形术(P<0.05)。结论:J型小贮袋术与结肠成形术均具有较高的安全性和可靠性,结肠J型小贮袋术具有足够的临床资料证明其远期疗效同样安全、有效。

Objective： To analyze the influence of different intestinal tract reconstruction after low ante- rior resection of rectal cancer on the function of defecation in the early stage and after the operation. Methods： Using database from Dec. 1995 to May 2016 published in line with the literature inclusion criteria were ran- domized controlled clinical trials were retrieved. Selected reconstruction success rate, anastomotic leakage and 24 hours defecation frequency as intraoperative. Results： Two ways in the operative mortality rate , 24 hours defecation frequency and incidence of anastomotie leakage （ P 〉 0.05 ） had no statistical significance .The fail- ure rate of colonic J pouch reconstruction was higher than that of colon （ P〈0.05 ）. Conclusion： CJP and TCP both have high safety and reliability, the CJP has enough clinical data to prove its long-term curative effect is equally safe and effective.