摘要
目的:确定具有神经保护作用新药的最佳水提取工艺参数。方法:采用L9(34)正交试验设计优选最佳工艺,以总皂苷和出膏率为综合评分指标,优选最佳水提取工艺,并对优选工艺进行验证。结果:最佳水提取工艺是10倍水,提取3次,每次提取1h。结论:优选后的水提取工艺稳定可靠,可为进一步开发利用该新药提供参考。
Objective To determine the process parameters of optimal water - extraction, which is Neuro Protective New - drug (NPN). Methods The process parameters were optimized by an orthogonal test L9 (3^4). Total saponins and the yield were selected as marker components and comprehensive weighted score was used to select and verify optimal process. Results The optimum water - extraction conditions was as follows: NPN was added with 10 times water, decocted for an hour for 3 times. Conclusion The optimized water - extraction and ethanol - extraction method is stable and reliable, and can provide reference for further development and utiliza- tion of the New - drug.
出处
《中国民族民间医药》
2016年第19期114-116,共3页
Chinese Journal of Ethnomedicine and Ethnopharmacy
基金
吉林省科技发展计划医药产业发展专项资金项目(NO.20130727032YY)
关键词
神经保护作用新药
正交试验
综合评分
Neuro Protective New- drug
Orhtogonal Test
Comprehensive Score