消化内科住院患者医院感染病原菌分布及耐药性分析

Pathogens distribution and resistance analysis of nosocomial infection in patients of department of gastroenterology

目的探讨消化内科住院患者医院感染的病原菌分布及耐药性,为临床上治疗消化内科住院患者发生医院感染提供依据。方法选取2014年2月-2015年6月在医院接受治疗180例消化内科医院感染患者作为研究对象,采用回顾性调查方式对其临床资料进行调查,分析患者感染的病原菌种类,对病原菌进行药敏试验并统计其耐药率。结果 180例感染患者共检出病原菌296株,其中革兰阳性菌112株占37.84%,革兰阴性菌184株占62.16%;溶血葡萄球菌、金黄色葡萄球菌和粪肠球菌对青霉素G的耐药性都是最高的,分别为92.86%、91.67%和94.44%;铜绿假单胞菌、鲍氏不动杆菌、肺炎克雷伯菌对环丙沙星的耐药性最高,分别为68.75%、64.29%和61.54%。结论消化内科患者住院时间长,治疗复杂,自身身体机能不全,免疫能力低下,易发生医院感染,感染率非常高,在临床治疗中值得重点关注。

OBJECTIVE To investigate the pathogens distribution and resistance of nosocomial infection in patients of department of gastroenterology,so as to provide theoretical guidance and basis for the clinical treatment of hospital infection of gastrointestinal hospitalized patients.METHODS A total of 180 cases of gastrointestinal patients with hospital infection from Feb.2014 to Jun.2015 were selected as study objects,and a retrospective survey method on clinical data of 180 cases was carried out.The types of pathogens were analyzed,and susceptibility experiment was carried out to analyzed the resistant rate.RESULTS Totally 296 strains of pathogens were isolated from 180 cases of infected patients,including 112 strains of gram-positive bacteria and 184 strains of gram-negative bacteria,accounting for 37.84% and 62.16%,respectively.Staphylococcus haemolyticus,Staphylococcus aureus and Enterococcus had the high resistant rate to penicillin G,accounting for 92.86%,91.67%and 94.44%,respectively.Pseudomonas aeruginosa,Acinetobacter baumannii,and Klebsiella pneumoniae had the high resistant rate to ciprofloxacin,accounting for 68.75%,64.29% and 61.54%,respectively.CONCLUSIONGastrointestinal inpatients have long hospital stay,complex treatment,combined with their physical insufficiency and low immunity,so they are prone to infection,and the infection rate is very high,it is worth focusing on clinical treatment.